Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 3/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | FOS | P01100 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26205650 | 0.88 | SLC7A5 (0.46) | NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL26206366 | 0.87 | PPARA (0.47) | CYSLTR2CYSLTR1FOSJUNCYP1A2 | |
| SCHEMBL26206374 | 0.85 | PPARA (0.51) | CYSLTR2CYSLTR1FOSJUNFFAR1 | |
| SCHEMBL22526755 | 0.82 | PPARA (0.42) | CYSLTR2CYSLTR1PPARGPPARA | |
| SCHEMBL11805244 | 0.81 | PLA2G4B (0.52) | NR1H3NR1H2PLA2G4BPPARDFOS | |
| SCHEMBL26205633 | 0.81 | HSD17B10 (0.48) | — | |
| SCHEMBL26205853 | 0.80 | HDAC1 (0.42) | PPARGPPARA | |
| SCHEMBL26206114 | 0.79 | HDAC1 (0.46) | PPARGPPARA | |
| SCHEMBL26206109 | 0.78 | HDAC1 (0.48) | PPARGPPARA | |
| SCHEMBL30169063 | 0.78 | ATM (0.42) | PLA2G4BCYP1A2CYP2C19PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | NR1H3 4116/4885NR1H2 3998/4885PLA2G4B 2786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.