Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.44 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.44 |
| ▸ | FOS | P01100 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26206374 | 0.95 | PPARA (0.51) | PPARAPPARGPTGIRCYSLTR2CYSLTR1 | |
| SCHEMBL22526755 | 0.91 | PPARA (0.42) | PPARAPPARGPTGIRCYSLTR2CYSLTR1 | |
| SCHEMBL26205853 | 0.89 | HDAC1 (0.42) | PPARAPPARGPTGIRCSF3RHDAC1 | |
| SCHEMBL26206408 | 0.87 | NR1H3 (0.45) | PPARAPPARGCYSLTR2CYSLTR1FOS | |
| SCHEMBL26206114 | 0.85 | HDAC1 (0.46) | PPARAPPARGCSF3RHDAC1HDAC6 | |
| SCHEMBL26206109 | 0.84 | HDAC1 (0.48) | PPARAPPARGCSF3RHDAC1HDAC6 | |
| SCHEMBL26206459 | 0.81 | FFAR1 (0.47) | CYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL26206480 | 0.81 | FFAR4 (0.39) | CSF3RFFAR1 | |
| SCHEMBL26205650 | 0.80 | SLC7A5 (0.46) | CYSLTR2CYSLTR1SMN1; SMN2 | |
| SCHEMBL22526731 | 0.80 | ATM (0.40) | PPARAPPARGPTGIRCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | PPARA 1856/4885PPARG 1830/4885PTGIR 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.