Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.54 |
| ▸ | TTR | P02766 | 6/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.48 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | EYA2 | O00167 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22072519 | 0.84 | TTR (0.46) | SLC22A12TTRCYP2C19NR1H4EYA3 | |
| SCHEMBL24221837 | 0.79 | CYP2C19 (0.47) | SLC22A12TTRCYP2C19NR1H4EYA3 | |
| SCHEMBL22680479 | 0.78 | TTR (0.43) | SLC22A12TTRCYP2C19NR1H4EYA3 | |
| SCHEMBL24102976 | 0.78 | CYP2C19 (0.46) | SLC22A12TTRCYP2C19NR1H4EYA3 | |
| SCHEMBL25815022 | 0.77 | CYP2C19 (0.79) | SLC22A12TTRCYP2C19NR1H4EYA3 | |
| SCHEMBL22658407 | 0.76 | CYP2C19 (0.55) | SLC22A12TTRCYP2C19NR1H4EYA3 | |
| SCHEMBL25815054 | 0.76 | SLC22A12 (0.67) | SLC22A12TTRCYP2C19NR1H4EYA3 | |
| SCHEMBL22658406 | 0.73 | CYP2C19 (0.51) | SLC22A12TTRCYP2C19NR1H4EYA3 | |
| SCHEMBL22072730 | 0.71 | SLC22A12 (0.88) | SLC22A12TTRCYP2C19NR1H4EYA3 | |
| SCHEMBL30258692 | 0.70 | TTR (0.68) | SLC22A12TTRCYP2C19NR1H4EYA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957629-B1 | PROCESS FOR MAKING DEUTERATED HYDROXY-BENZBROMARONE AND INTERMEDIATES THEREOF | ARTHROSI THERAPEUTICS INC (US) | 2023-09-06 | — | — | EP | disclosed |