Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.88 |
| ▸ | TTR | P02766 | 6/20 | 0.73 |
| ▸ | EYA3 | Q99504 | 5/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | PGR | P06401 | 2/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.70 |
| ▸ | EYA2 | O00167 | 1/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25814819 | 0.91 | SLC22A12 (0.73) | SLC22A12TTREYA3CYP2C19CYP2C9 | |
| SCHEMBL20280676 | 0.87 | SLC22A12 (0.75) | SLC22A12TTREYA3CYP2C19CYP2C9 | |
| SCHEMBL30357377 | 0.84 | SLC22A12 (0.81) | SLC22A12TTREYA3CYP2C19CYP2C9 | |
| SCHEMBL30357404 | 0.84 | SLC22A12 (0.81) | SLC22A12TTREYA3CYP2C19CYP2C9 | |
| SCHEMBL1287499 | 0.84 | SLC22A12 (1.00) | SLC22A12TTREYA3CYP2C19CYP2C9 | |
| SCHEMBL1288090 | 0.84 | SLC22A12 (1.00) | SLC22A12TTREYA3CYP2C19CYP2C9 | |
| SCHEMBL1287650 | 0.84 | SLC22A12 (0.74) | SLC22A12TTREYA3CYP2C19CYP2C9 | |
| SCHEMBL15698041 | 0.83 | SLC22A12 (0.80) | SLC22A12TTREYA3CYP2C19CYP2C9 | |
| SCHEMBL30258709 | 0.83 | SLC22A12 (0.80) | SLC22A12TTREYA3CYP2C19CYP2C9 | |
| SCHEMBL30258695 | 0.83 | SLC22A12 (0.80) | SLC22A12TTREYA3CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218563-A1 | METHODS FOR TREATING OR PREVENTING CHRONIC KIDNEY DISEASE | ARTHROSI THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230218563-A1 | METHODS FOR TREATING OR PREVENTING CHRONIC KIDNEY DISEASE | ARTHROSI THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| WO-2023098872-A1 | CRYSTALLINE FORMS OF A COMPOUND FOR TREATING OR PREVENTING GOUT OR HYPERURICEMIA | ARTHROSI THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | WO | disclosed |
| US-20220024889-A1 | CRYSTALLINE FORMS OF A COMPOUND FOR TREATING OR PREVENTING GOUT OR HYPERURICEMIA | ARTHROSI THERAPEUTICS, INC. | 2022-01-27 | — | — | US | disclosed |
| US-20220023251-A1 | METHODS FOR TREATING OR PREVENTING GOUT OR HYPERURICEMIA | ARTHROSI THERAPEUTICS, INC. | 2022-01-27 | — | — | US | disclosed |
| WO-2021252630-A1 | METHODS FOR TREATING OR PREVENTING CHRONIC KIDNEY DISEASE | ARTHROSI THERAPEUTICS, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
| WO-2020232156-A1 | COMPOUND FOR TREATING GOUT OR HYPERURICEMIA | ARTHROSI THERAPEUTICS, INC. (US) | 2020-11-19 | — | — | WO | disclosed |
| WO-2020118113-A1 | CRYSTALLINE FORMS OF A COMPOUND FOR TREATING OR PREVENTING GOUT OR HYPERURICEMIA | ARTHROSI THERAPEUTICS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020118114-A1 | METHODS FOR TREATING OR PREVENTING GOUT OR HYPERURICEMIA | ARTHROSI THERAPEUTICS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024889-A1 | CRYSTALLINE FORMS OF A COMPOUND FOR TREATING OR PREVENTING GOUT OR HYPERURICEMIA | CYP27A1, CYP24A1, CYP27B1 | SLC22A12 854/4885TTR 117/4885EYA3 4702/4885 |
| US-20220023251-A1 | METHODS FOR TREATING OR PREVENTING GOUT OR HYPERURICEMIA | CYP27B1, XDH, CYP27A1 | SLC22A12 830/4885TTR 189/4885EYA3 4761/4885 |
| US-20230218563-A1 | METHODS FOR TREATING OR PREVENTING CHRONIC KIDNEY DISEASE | ATP6V1B1, REN, CYP27B1 | SLC22A12 620/4885TTR 201/4885EYA3 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.