Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.49 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19574920 | 1.00 | ADORA2A (0.49) | ADORA2AADCY5ADORA2BADORA1LMNA | |
| SCHEMBL19575371 | 0.89 | TMIGD3 (0.41) | ADORA2AADORA2BADORA1LMNASMN1; SMN2 | |
| SCHEMBL26212223 | 0.89 | TMIGD3 (0.41) | ADORA2AADORA2BADORA1LMNASMN1; SMN2 | |
| SCHEMBL19575403 | 0.87 | ADCY5 (0.51) | ADORA2AADCY5ADORA1LMNASMN1; SMN2 | |
| SCHEMBL20972815 | 0.87 | ADCY5 (0.51) | ADORA2AADCY5ADORA1LMNASMN1; SMN2 | |
| SCHEMBL19575639 | 0.87 | HDAC1 (0.42) | ADORA2AADORA2BADORA1 | |
| SCHEMBL19575642 | 0.87 | SERPINA3 (0.47) | ADORA2AADORA2BADORA1LMNASMN1; SMN2 | |
| SCHEMBL26212252 | 0.87 | SERPINA3 (0.47) | ADORA2AADORA2BADORA1LMNASMN1; SMN2 | |
| SCHEMBL26212539 | 0.87 | HDAC1 (0.42) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20975164 | 0.84 | HDAC1 (0.43) | ADORA2AADORA2BADORA1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452477-B1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B C I PHARMA (BE) | 2023-09-13 | — | — | EP | disclosed |