Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20972815 | 1.00 | ADCY5 (0.51) | ADCY5LMNASMN1; SMN2HPGDADORA2A | |
| SCHEMBL20973538 | 0.92 | LMNA (0.53) | ADCY5LMNASMN1; SMN2HPGDADORA2A | |
| SCHEMBL20974516 | 0.91 | NSD3 (0.53) | ADCY5LMNASMN1; SMN2HPGDADORA2A | |
| SCHEMBL19575471 | 0.91 | NSD3 (0.53) | ADCY5LMNASMN1; SMN2HPGDADORA2A | |
| SCHEMBL19575394 | 0.91 | NSD3 (0.53) | ADCY5LMNASMN1; SMN2HPGDADORA2A | |
| SCHEMBL20975139 | 0.90 | NSD3 (0.57) | ADCY5LMNASMN1; SMN2ADORA2ANSD3 | |
| SCHEMBL26212056 | 0.89 | ADCY5 (0.46) | ADCY5LMNASMN1; SMN2HPGDADORA2A | |
| SCHEMBL19575472 | 0.89 | ADCY5 (0.46) | ADCY5LMNASMN1; SMN2HPGDADORA2A | |
| SCHEMBL26212177 | 0.87 | ADORA2A (0.49) | ADCY5LMNASMN1; SMN2HPGDADORA2A | |
| SCHEMBL19574920 | 0.87 | ADORA2A (0.49) | ADCY5LMNASMN1; SMN2HPGDADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017191297-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | BCI PHARMA (FR) | 2017-11-09 | — | — | WO | disclosed |