⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4211437 | 0.81 | KMT2A (0.32) | — | |
| SCHEMBL27570211 | 0.76 | — | — | |
| SCHEMBL24050962 | 0.75 | — | — | |
| SCHEMBL10481210 | 0.74 | — | — | |
| SCHEMBL680606 | 0.74 | — | — | |
| SCHEMBL29899254 | 0.72 | — | — | |
| SCHEMBL12817376 | 0.70 | — | — | |
| SCHEMBL27256470 | 0.70 | KDM4E (0.33) | — | |
| SCHEMBL3082762 | 0.67 | NPC1 (0.42) | — | |
| SCHEMBL13236412 | 0.67 | CYP1A2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621864-A | Boron ester furan derivative compound and preparation method and application thereof | 陕西师范大学 | 2023-08-22 | — | — | CN | claimed |
| CN-112898285-B | Trifluoromethyl-containing bisoxazole compound, and synthesis method and application thereof in anti-cancer drugs | 河南师范大学 | 2022-05-24 | — | — | CN | claimed |
| CN-106660994-A | Phosphatidylinositol 3-kinase inhibitors | 吉利德科学公司 | 2017-05-10 | — | — | CN | claimed |
| CN-102911131-B | Double-bond trifluoromethyl isoxazole compound, preparation method and application thereof | Sinochem Lantian Co., Ltd. (CN) | 2014-10-29 | — | — | CN | claimed |
| CN-102911131-A | Double-bond trifluoromethyl isoxazole compound, preparation method and application thereof | SINOCHEM LANTIAN CO LTD | 2013-02-06 | — | — | CN | claimed |
| CN-116621864-B | Boron ester furan derivative compound and preparation method and application thereof | 陕西师范大学 | 2025-09-12 | — | — | CN | disclosed |
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| US-20250129044-A1 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | XENON PHARMACEUTICALS INC. (CA) | 2025-04-24 | — | — | US | disclosed |
| US-12202826-B2 | N-pyridinyl acetamide derivatives as inhibitors of the Wnt signaling pathway | REDX PHARMA PLC (GB) | 2025-01-21 | — | — | US | disclosed |
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-01-02 | — | — | US | disclosed |
| US-20240336592-A1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA PLC (GB) | 2024-10-10 | — | — | US | disclosed |
| US-20240208992-A1 | MACROCYCLES AS CFTR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-27 | — | — | US | disclosed |
| WO-1998028282-A2 | OXYGEN OR SULFUR CONTAINING 5-MEMBERED HETEROAROMATICS AS FACTOR Xa INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| EP-0699191-A1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994027979-A1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | IMMUNOPHARMACEUTICS, INC. (US) | 1994-12-08 | — | — | WO | disclosed |
| EP-0245825-B1 | STYRYL PYRAZOLES, ISOXAZOLES AND ANALOGS THEREOF HAVING ACTIVITY AS 5-LIPOXY-GENASE INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WARNER-LAMBERT COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0371876-A1 | Isoxazoles and isoxazolines with an anticonvulsive activity, and pharmaceutical compositions containing them | NOVAPHARME (FR) | 1990-06-06 | — | — | EP | disclosed |
| US-4906277-A | Isoxazoline derivatives and plant growth regulators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-03-06 | — | — | US | disclosed |
| US-4889551-A | Isoxazoline derivatives and plant growth regulators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1989-12-26 | — | — | US | disclosed |
| EP-0270963-A1 | Fluor-containing 5-trihalogen methyl isoxazoles, and method for their preparation | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |