⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27729812 | 0.97 | RAB9A (0.32) | — | |
| SCHEMBL27256470 | 0.80 | KDM4E (0.33) | — | |
| SCHEMBL12817376 | 0.80 | — | — | |
| SCHEMBL14026632 | 0.77 | CYP1A2 (0.36) | — | |
| SCHEMBL13236412 | 0.77 | CYP1A2 (0.40) | — | |
| SCHEMBL29899254 | 0.77 | — | — | |
| SCHEMBL27570211 | 0.76 | — | — | |
| SCHEMBL11493274 | 0.75 | TAAR1 (0.39) | — | |
| SCHEMBL29899227 | 0.75 | CYP1A2 (0.32) | — | |
| SCHEMBL16174569 | 0.75 | JAK2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 820 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354630-B | 5,6-dihydrobenzo [ h ] quinazoline compound and application thereof | 江南大学 | 2022-11-01 | — | — | CN | claimed |
| CN-113354630-A | 5, 6-dihydrobenzo [ h ] quinazoline compound and application thereof | 江南大学 | 2021-09-07 | — | — | CN | claimed |
| EP-0101034-B1 | METHOD FOR PREPARING 3-AMINO-5-(SUBSTITUTED)ISOXAZOLE | PPG INDUSTRIES, INC. (US) | 1986-10-22 | — | — | EP | claimed |
| US-12202826-B2 | N-pyridinyl acetamide derivatives as inhibitors of the Wnt signaling pathway | REDX PHARMA PLC (GB) | 2025-01-21 | — | — | US | disclosed |
| US-12043623-B2 | Purinones as ubiquitin-specific protease 1 inhibitors | FORMA THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-12036209-B2 | Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides | ARVINAS OPERATIONS, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12036209-B2 | Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides | ARVINAS OPERATIONS, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12024525-B2 | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment | AGENEBIO, INC. (US) | 2024-07-02 | — | — | US | disclosed |
| US-12024500-B2 | Five-membered ring-substituted pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2024-07-02 | — | — | US | disclosed |
| US-20240067673-A1 | MODIFIED NUCLEOSIDE OR NUCLEOTIDE | BGI SHENZHEN (CN) | 2024-02-29 | — | — | US | disclosed |
| US-20240067673-A1 | MODIFIED NUCLEOSIDE OR NUCLEOTIDE | BGI SHENZHEN (CN) | 2024-02-29 | — | — | US | disclosed |
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE, INC. | 2007-01-04 | — | — | US | disclosed |
| US-20060025415-A1 | Compositions useful as inhibitors of voltage-gated sodium channels | VERTEX PHARMACEUTICALS INCORPORATED | 2006-02-02 | — | — | US | disclosed |
| US-20060025416-A1 | Substituted aryl acylthioureas and related compounds; inhibitors of viral replication | ACHILLION PHARMACEUTICALS, INC. | 2006-02-02 | — | — | US | disclosed |
| EP-0870764-A1 | Sulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| EP-0046193-B1 | 1-HYDROXYPYRAZOLE AND PROCESS FOR PREPARING THE SAME | BASF Aktiengesellschaft (DE) | 1983-09-28 | — | — | EP | disclosed |
| EP-0010262-B1 | PROCESS FOR PREPARING 3-AMINO-5-T-BUTYLISOXAZOLE | SHIONOGI & CO., LTD. (JP) | 1983-01-26 | — | — | EP | disclosed |
| US-4350819-A | 1-Hydroxypyrazole | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |
| EP-0046193-A1 | 1-Hydroxypyrazole and process for preparing the same | BASF Aktiengesellschaft (DE) | 1982-02-24 | — | — | EP | disclosed |
| EP-0010262-A1 | Process for preparing 3-amino-5-t-butylisoxazole | SHIONOGI & CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |