SCHEMBL26214723

SCHEMBL26214723

COC[C@H]1[C@@H](O)[C@H](n2c[n+](C)c3c(=O)[nH]c(N)nc32)O[C@@H]1COP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](OC)[C@@H]1OP(=O)([O-])OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](OC)[C@@H]1O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RNASEL Q05823 7/20 0.56
P2RY2 P41231 4/20 0.53
P2RY4 P51582 1/20 0.50
P2RY6 Q15077 1/20 0.50
P2RY1 P47900 4/20 0.46
SRC P12931 1/20 0.46
P2RX1 P51575 1/20 0.46
P2RX3 P56373 1/20 0.46
P2RX4 Q99571 1/20 0.46
P2RX2 Q9UBL9 1/20 0.46
ALDH1A1 P00352 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
DTYMK P23919 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26201729 0.98 RNASEL (0.58) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26206302 0.96 RNASEL (0.58) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26202441 0.96 RNASEL (0.61) RNASELP2RY2P2RY4P2RY6
SCHEMBL26214226 0.95 RNASEL (0.56) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26202067 0.95 RNASEL (0.56) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26214231 0.95 RNASEL (0.56) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26214217 0.95 RNASEL (0.55) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26579101 0.94 RNASEL (0.57) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26213497 0.94 RNASEL (0.63) RNASELP2RY2P2RY4P2RY6P2RY1
SCHEMBL26212708 0.94 RNASEL (0.57) RNASELP2RY2P2RY4P2RY6P2RY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed