SCHEMBL26224291

SCHEMBL26224291

CC(C)(C)c1ccc(-c2ncnc3ccccc23)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.66
GRM4 Q14833 1/20 0.46
TNKS O95271 1/20 0.46
TNKS2 Q9H2K2 1/20 0.46
KMT2A Q03164 3/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
PIK3CD O00329 1/20 0.43
PIK3CA P42336 1/20 0.43
PIK3CB P42338 1/20 0.43
MTOR P42345 1/20 0.43
PIK3CG P48736 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
TNF P01375 1/20 0.43
NOD1 Q9Y239 1/20 0.43
PDGFRB P09619 1/20 0.43
KIT P10721 1/20 0.43
FLT3 P36888 1/20 0.43
BTK Q06187 1/20 0.43
MAP3K19 Q56UN5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29986864 1.00 ADORA2A (0.66) ADORA2AGRM4TNKSTNKS2KMT2A
SCHEMBL29986586 0.83 ADORA2A (0.66) ADORA2AGRM4TNKSTNKS2KMT2A
SCHEMBL699076 0.83 ADORA2A (0.66) ADORA2AGRM4TNKSTNKS2KMT2A
SCHEMBL29986490 0.81 ADORA2A (0.72) ADORA2AGRM4KMT2AKDM4EALDH1A1
SCHEMBL12357140 0.81 ADORA2A (0.72) ADORA2AGRM4KMT2AKDM4EALDH1A1
Hydrochloric Acid SCHEMBL29187356 0.81 ADORA2A (0.62) ADORA2AGRM4TNKSTNKS2PIK3CD
Hydrochloric Acid SCHEMBL30788683 0.81 ADORA2A (0.62) ADORA2AGRM4TNKSTNKS2PIK3CD
SCHEMBL29986426 0.80 ADORA2A (0.92) ADORA2AGRM4KMT2AKDM4EALDH1A1
SCHEMBL15815414 0.80 ADORA2A (0.92) ADORA2AGRM4KMT2AKDM4EALDH1A1
SCHEMBL24795192 0.80 ADORA2A (0.53) ADORA2AGRM4PIK3CDPIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4243101-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
EP-4242205-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
CN-110078675-B 4-aryl quinazoline compound and preparation method thereof 郑州大学 2022-09-23 CN disclosed