Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.66 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986586 | 1.00 | ADORA2A (0.66) | ADORA2AABCG2EGFRKDRTSHR | |
| Hydrochloric Acid SCHEMBL30788683 | 0.97 | ADORA2A (0.62) | ADORA2AABCG2EGFRKDRTSHR | |
| Hydrochloric Acid SCHEMBL29187356 | 0.97 | ADORA2A (0.62) | ADORA2AABCG2EGFRKDRTSHR | |
| SCHEMBL30788658 | 0.94 | ADORA2A (0.58) | ADORA2AABCG2EGFRKDRTSHR | |
| SCHEMBL29986864 | 0.83 | ADORA2A (0.66) | ADORA2AABCG2KDRKIF11GRM4 | |
| SCHEMBL26224291 | 0.83 | ADORA2A (0.66) | ADORA2AABCG2KDRKIF11GRM4 | |
| SCHEMBL31022035 | 0.81 | ADORA2A (0.58) | ADORA2ATSHRGRM4AAK1MEN1 | |
| SCHEMBL17666810 | 0.81 | ADORA2A (0.72) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29986591 | 0.81 | ADORA2A (0.72) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL15815414 | 0.80 | ADORA2A (0.92) | ADORA2AABCG2EGFRHTTGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421848-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2012-02-29 | — | — | EP | claimed |
| WO-2010124119-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-28 | — | — | WO | claimed |
| CN-117510553-A | Diphenyl phosphinic amide luminescent iridium complex, preparation method thereof and application thereof in organic electroluminescent device | 安徽秀朗新材料科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-110078675-B | 4-aryl quinazoline compound and preparation method thereof | 郑州大学 | 2022-09-23 | — | — | CN | disclosed |