Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18537507 | 0.87 | CA1 (0.37) | NOS1NOS2CA1CA2CA4 | |
| SCHEMBL16411367 | 0.85 | CA1 (0.38) | NOS1NOS2CA1CA2CA4 | |
| SCHEMBL22420199 | 0.78 | — | — | |
| SCHEMBL22416877 | 0.77 | NOS3 (0.33) | NOS1NOS2 | |
| SCHEMBL18519081 | 0.77 | CA1 (0.31) | CA1CA2CA4 | |
| SCHEMBL18537462 | 0.71 | NOS3 (0.33) | NOS1NOS2 | |
| SCHEMBL18789486 | 0.69 | — | — | |
| SCHEMBL26263984 | 0.68 | CA1 (0.31) | NOS1NOS2CA1CA2CA4 | |
| SCHEMBL24771678 | 0.68 | EPHX2 (0.34) | NOS1NOS2 | |
| SCHEMBL10000912 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4242307-A2 | SIRT1-SARNA COMPOSITIONS AND METHODS OF USE | MiNA Therapeutics Limited (GB) | 2023-09-13 | — | — | EP | disclosed |