Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.31 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.31 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.31 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | LGMN | Q99538 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26229976 | 0.96 | POLRMT (0.46) | POLRMTDOT1LTNK2STING1RIPK1 | |
| SCHEMBL26229811 | 0.95 | POLRMT (0.46) | POLRMTDOT1LTNK2STING1PIK3CD | |
| SCHEMBL26230753 | 0.94 | POLRMT (0.47) | POLRMTDOT1LTNK2STING1RIPK1 | |
| SCHEMBL26230098 | 0.90 | POLRMT (0.48) | POLRMTDOT1LTNK2STING1RIPK1 | |
| SCHEMBL26230341 | 0.89 | POLRMT (0.49) | POLRMTDOT1LSTING1RIPK1PIK3CD | |
| SCHEMBL26238995 | 0.88 | POLRMT (0.48) | POLRMTDOT1LSTING1RIPK1CSNK2A2 | |
| SCHEMBL26230093 | 0.88 | POLRMT (0.48) | POLRMTDOT1LSTING1RIPK1 | |
| SCHEMBL26832849 | 0.87 | POLRMT (0.46) | POLRMTDOT1LSTING1RIPK1CSNK2A2 | |
| SCHEMBL26229975 | 0.87 | POLRMT (0.47) | POLRMTDOT1LSTING1RIPK1 | |
| SCHEMBL26235400 | 0.87 | POLRMT (0.47) | POLRMTDOT1LSTING1RIPK1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168194-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |