SCHEMBL2623249

SCHEMBL2623249

[3H]c1cccc(-c2ccc(N(c3ccccc3)c3cccc(-c4cccc(-c5cc(-c6ccccc6)cc(-c6cccc(-c7cccc(N(c8ccccc8)c8ccc(-c9cccc([3H])c9)cc8)c7)c6)n5)c4)c3)cc2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.38
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
MCL1 Q07820 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CRHR1 P34998 1/20 0.32
MYC P01106 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
GLA P06280 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
AKT1 P31749 1/20 0.32
AKT2 P31751 1/20 0.32
AKT3 Q9Y243 1/20 0.32
LTB4R Q15722 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2623244 0.90 ALDH1A1 (0.37) MEN1KMT2AESR1MCL1NPC1
SCHEMBL2623297 0.87 CYP19A1 (0.42) CYP19A1MEN1KMT2AESR1ESR2
SCHEMBL2623308 0.87 ALDH1A1 (0.37) MEN1KMT2AESR1MCL1NPC1
SCHEMBL12258371 0.85 MEN1 (0.45) CYP19A1MEN1KMT2ARAB9AKDM4E
SCHEMBL2623248 0.85 ALDH1A1 (0.41) MEN1KMT2AESR1KDM4EALDH1A1
SCHEMBL2623293 0.84 ALDH1A1 (0.39) MEN1KMT2AESR1MCL1NPC1
SCHEMBL2623234 0.84 MEN1 (0.39) MEN1KMT2AESR1ESR2KDM4E
SCHEMBL2623228 0.84 MEN1 (0.39) MEN1KMT2AESR1ESR2KDM4E
SCHEMBL14426238 0.82 MEN1 (0.48) CYP19A1MEN1KMT2AMCL1RAB9A
SCHEMBL21974098 0.82 CYP19A1 (0.49) CYP19A1MEN1KMT2AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120091443-A1 COMPOSITION FOR USE IN ORGANIC DEVICE, POLYMER FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2012-04-19 US disclosed
US-20100045174-A1 COMPOSITION FOR USE IN ORGANIC DEVICE, POLYMER FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2010-02-25 US disclosed