Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23528438 | 0.92 | MET (0.43) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL23528304 | 0.91 | MET (0.43) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL29569490 | 0.91 | MET (0.43) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL23558981 | 0.91 | MET (0.45) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL23528280 | 0.91 | MET (0.43) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL26528269 | 0.90 | MET (0.42) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL23528428 | 0.89 | MET (0.41) | METGRIN1GRIN2BMEN1KMT2A | |
| Sevasemten SCHEMBL23528413 | 0.89 | MET (0.42) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL23528368 | 0.87 | MET (0.45) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL23528328 | 0.86 | PDE4A (0.47) | METGRIN1GRIN2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4248973-A2 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2023-09-27 | — | — | EP | disclosed |
| EP-3877376-B1 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS INC (US) | 2023-08-23 | — | — | EP | disclosed |