Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.37 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26832526 | 0.91 | POLRMT (0.35) | POLRMTDOT1LRIPK1 | |
| SCHEMBL26235338 | 0.90 | POLRMT (0.35) | POLRMTDOT1L | |
| SCHEMBL26235537 | 0.90 | POLRMT (0.36) | POLRMTDOT1L | |
| SCHEMBL26235390 | 0.89 | POLRMT (0.35) | POLRMTDOT1L | |
| SCHEMBL26235392 | 0.88 | POLRMT (0.35) | POLRMTDOT1L | |
| SCHEMBL26235533 | 0.88 | POLRMT (0.35) | POLRMTDOT1L | |
| SCHEMBL26235613 | 0.88 | POLRMT (0.36) | POLRMTDOT1LRIPK1 | |
| SCHEMBL26235397 | 0.88 | POLRMT (0.35) | POLRMTDOT1L | |
| SCHEMBL26235336 | 0.88 | POLRMT (0.34) | POLRMTDOT1LPIK3CDCSNK2A2CSNK2A1 | |
| SCHEMBL26235530 | 0.88 | POLRMT (0.36) | POLRMTDOT1LRIPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168254-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |