SCHEMBL26236754

SCHEMBL26236754

CCC(C)CCCCC(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22435117 0.98 LMNA (0.33) LMNA
SCHEMBL12650148 0.93 MEN1 (0.31) LMNA
SCHEMBL26318602 0.85
SCHEMBL15160264 0.85
SCHEMBL15786557 0.85
SCHEMBL18411735 0.82 ACE2 (0.38) LMNA
SCHEMBL1805229 0.79 LMNA (0.50) LMNA
SCHEMBL8949649 0.78 LMNA (0.36) LMNA
SCHEMBL12251777 0.77 LMNA (0.46) LMNA
SCHEMBL20376061 0.76 ACE2 (0.41) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3159344-B1 AMINO PYRANOID RING DERIVATIVE AND COMPOSITION AND USE THEREOF SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN) 2023-09-20 EP disclosed