Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838152 | 0.77 | HTT (0.58) | HTTPOLBFGFR1 | |
| SCHEMBL3417306 | 0.75 | HTT (0.73) | HTTPOLBFGFR1ROCK1MKNK1 | |
| SCHEMBL3419279 | 0.75 | HTT (0.88) | HTTPOLBFGFR1 | |
| SCHEMBL30402227 | 0.75 | HTT (0.88) | HTTPOLBFGFR1 | |
| SCHEMBL9464658 | 0.74 | HTT (0.55) | HTTPOLBFGFR1ROCK1MKNK1 | |
| SCHEMBL13052913 | 0.74 | HTT (0.77) | HTTPOLBFGFR1 | |
| SCHEMBL157265 | 0.74 | HTT (1.00) | HTTFGFR1 | |
| SCHEMBL9025863 | 0.74 | PIK3CB (0.68) | HTTPOLBFGFR1ROCK1MKNK1 | |
| Benzene SCHEMBL14876970 | 0.74 | HTT (1.00) | HTTFGFR1 | |
| SCHEMBL13196562 | 0.73 | HTT (0.58) | HTTPOLBFGFR1ROCK1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9066410-B2 | Organic electronic device | MERCK PATENT GMBH (DE) | 2015-06-23 | — | — | US | disclosed |
| US-9066410-B2 | Organic electronic device | MERCK PATENT GMBH (DE) | 2015-06-23 | — | — | US | disclosed |
| US-20120091884-A1 | HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AT) | 2012-04-19 | — | — | US | disclosed |
| US-20120091884-A1 | HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AT) | 2012-04-19 | — | — | US | disclosed |
| WO-2010132953-A1 | HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120091884-A1 | HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE | HSD17B2, CYP1A2, HSD17B1 | HTT 2018/4885POLB 3679/4885FGFR1 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.