Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.63 |
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.61 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.61 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26238244 | 1.00 | USP2 (0.64) | USP2GPBAR1NR1H4CYP3A4PDE3A | |
| Cholate SCHEMBL18485247 | 0.90 | GPBAR1 (0.64) | GPBAR1NR1H4CYP3A4PDE3ASLC10A2 | |
| Cholate SCHEMBL18472024 | 0.90 | GPBAR1 (0.64) | GPBAR1NR1H4CYP3A4PDE3ASLC10A2 | |
| Cholate SCHEMBL12568048 | 0.90 | GPBAR1 (0.64) | GPBAR1NR1H4CYP3A4PDE3ASLC10A2 | |
| Cholate SCHEMBL19273280 | 0.90 | GPBAR1 (0.64) | GPBAR1NR1H4CYP3A4PDE3ASLC10A2 | |
| Cholate SCHEMBL19268301 | 0.90 | GPBAR1 (0.64) | GPBAR1NR1H4CYP3A4PDE3ASLC10A2 | |
| SCHEMBL22435827 | 0.89 | USP2 (0.61) | USP2GPBAR1NR1H4CYP3A4PDE3A | |
| SCHEMBL24229482 | 0.88 | USP2 (0.82) | USP2GPBAR1NR1H4CYP3A4PDE3A | |
| SCHEMBL19135895 | 0.81 | USP2 (0.60) | USP2GPBAR1NR1H4CYP3A4SLC10A2 | |
| SCHEMBL12568064 | 0.80 | GPBAR1 (0.52) | GPBAR1NR1H4CYP3A4PDE3ASLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348457-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL LTD (CN) | 2023-11-02 | — | — | US | disclosed |
| US-20230348457-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL LTD (CN) | 2023-11-02 | — | — | US | disclosed |
| US-20230295151-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| US-20230295151-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348457-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | CYP27A1, NR1H4, CYP7A1 | USP2 4771/4885GPBAR1 12/4885NR1H4 2/4885 |
| US-20230295151-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | CYP27A1, NR1H4, CYP7A1 | USP2 4771/4885GPBAR1 12/4885NR1H4 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.