Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 9/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22526445 | 0.91 | DDB1 (0.53) | DDB1CRBNNR1H4CSF1R | |
| SCHEMBL29382024 | 0.91 | DDB1 (0.53) | DDB1CRBNNR1H4CSF1R | |
| SCHEMBL31701392 | 0.81 | DDB1 (0.43) | DDB1CRBNNR1H4CSF1R | |
| SCHEMBL22502706 | 0.77 | CRBN (0.60) | DDB1CRBNKDM4E | |
| SCHEMBL25952683 | 0.77 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL29320658 | 0.77 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL30304339 | 0.75 | DDB1 (0.54) | DDB1CRBNKDM4E | |
| SCHEMBL31068547 | 0.75 | NR1H4 (0.36) | NR1H4CSF1RESR1HDAC1 | |
| SCHEMBL30990758 | 0.75 | CRBN (0.54) | DDB1CRBN | |
| SCHEMBL25036954 | 0.75 | BRD4 (0.43) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | DDB1 3993/4885CRBN 171/4885NR1H4 2667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.