Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 18/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29382024 | 0.90 | DDB1 (0.53) | DDB1CRBNNR1H4CSF1R | |
| SCHEMBL22526445 | 0.90 | DDB1 (0.53) | DDB1CRBNNR1H4CSF1R | |
| SCHEMBL31700551 | 0.82 | DDB1 (0.38) | DDB1CRBNNR1H4CSF1R | |
| SCHEMBL26238548 | 0.81 | DDB1 (0.42) | DDB1CRBNNR1H4CSF1R | |
| SCHEMBL31702322 | 0.79 | CRBN (0.51) | DDB1CRBN | |
| SCHEMBL31273627 | 0.77 | CRBN (0.58) | DDB1CRBN | |
| SCHEMBL30273466 | 0.77 | DDB1 (0.54) | DDB1CRBN | |
| SCHEMBL22502706 | 0.76 | CRBN (0.60) | DDB1CRBN | |
| SCHEMBL31305140 | 0.75 | CRBN (0.58) | DDB1CRBN | |
| SCHEMBL30006290 | 0.75 | CRBN (0.58) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014147-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-20250325677-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250320206-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | DDB1 3966/4885CRBN 1627/4885NR1H4 1481/4885 |
| US-20260014147-A1 | STAT6 DEGRADERS | STAT6, NCOR1, CBR1 | DDB1 3708/4885CRBN 133/4885NR1H4 278/4885 |
| US-20250320206-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | DDB1 3966/4885CRBN 1627/4885NR1H4 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.