Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26241444 | 0.88 | POLRMT (0.39) | POLRMTDOT1LRIPK1 | |
| SCHEMBL26229927 | 0.87 | POLRMT (0.41) | POLRMTDOT1LRIPK1STING1PIK3CD | |
| SCHEMBL26239930 | 0.87 | POLRMT (0.39) | POLRMTDOT1LRIPK1STING1PIK3CD | |
| SCHEMBL26229924 | 0.86 | POLRMT (0.40) | POLRMTDOT1LRIPK1PIK3CD | |
| SCHEMBL26229814 | 0.85 | POLRMT (0.39) | POLRMTDOT1LRIPK1 | |
| SCHEMBL26229808 | 0.85 | POLRMT (0.40) | POLRMTDOT1L | |
| SCHEMBL26239590 | 0.84 | POLRMT (0.37) | POLRMTDOT1LGRM5STING1PIK3CD | |
| SCHEMBL26229810 | 0.84 | POLRMT (0.40) | POLRMTDOT1LRIPK1 | |
| SCHEMBL26832289 | 0.83 | POLRMT (0.35) | POLRMT | |
| SCHEMBL26230172 | 0.82 | POLRMT (0.38) | POLRMTDOT1LRIPK1STING1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168254-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |