Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.57 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26242002 | 0.92 | HRH3 (0.59) | HRH3ELANEKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL26240558 | 0.89 | HRH3 (0.57) | HRH3ELANEKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL26242004 | 0.87 | HRH3 (0.55) | HRH3ELANEKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL26241987 | 0.85 | HRH3 (0.53) | HRH3ELANEKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL26240548 | 0.74 | HRH3 (0.57) | HRH3ELANEKMT2AKDM4EMEN1 | |
| SCHEMBL3386983 | 0.73 | HRH3 (1.00) | HRH3ELANE | |
| SCHEMBL3386053 | 0.70 | HRH3 (1.00) | HRH3 | |
| SCHEMBL7424821 | 0.62 | HRH3 (0.59) | HRH3ELANEKMT2ARAB9ACACNA1G | |
| SCHEMBL3382832 | 0.61 | HRH3 (0.61) | HRH3ELANEKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL7424959 | 0.61 | HRH3 (0.57) | HRH3ELANEKMT2ARAB9ACACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023171448-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASE TO BE PREVENTED OR TREATED BY DEACTIVATION OF MYOFIBROBLASTS | 学校法人東海大学 | 2023-09-14 | — | — | WO | disclosed |