Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424821 | 0.98 | HRH3 (0.59) | HRH3ELANEL3MBTL1GSK3BCACNA1G | |
| SCHEMBL3382832 | 0.97 | HRH3 (0.61) | HRH3ELANEL3MBTL1GSK3BCACNA1G | |
| SCHEMBL3384305 | 0.86 | HRH3 (0.62) | HRH3GSK3BCACNA1GKCNH2CYP2C9 | |
| Potassium Ion SCHEMBL7424963 | 0.83 | HRH3 (0.56) | HRH3ELANEL3MBTL1GSK3BCACNA1G | |
| Potassium Ion SCHEMBL7427991 | 0.83 | HRH3 (0.56) | HRH3ELANEL3MBTL1GSK3BCACNA1G | |
| SCHEMBL7427115 | 0.81 | HRH3 (0.57) | HRH3ELANEGSK3BCACNA1GKCNH2 | |
| SCHEMBL7425000 | 0.80 | DRD4 (0.51) | HRH3CACNA1GKMT2A | |
| SCHEMBL12965742 | 0.80 | GSK3B (0.48) | HRH3ELANEGSK3BCACNA1GKCNH2 | |
| SCHEMBL7421852 | 0.80 | HRH3 (0.59) | HRH3ELANEGSK3BCACNA1GKCNH2 | |
| SCHEMBL7423841 | 0.79 | HRH3 (0.55) | HRH3ELANECACNA1GKCNH2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000053589-A1 | PROCESS FOR PREPARING OXAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-09-14 | — | — | WO | claimed |
| WO-2000053589-A1 | PROCESS FOR PREPARING OXAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-09-14 | — | — | WO | disclosed |