Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KYNU | Q16719 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262466 | 1.00 | CTSL (0.44) | CTSLSYKCTRB1CTSBCTSS | |
| SCHEMBL2796603 | 0.92 | SYK (0.44) | CTSLSYKCTRB1CTSBCTSS | |
| SCHEMBL2796597 | 0.92 | SYK (0.44) | CTSLSYKCTRB1CTSBCTSS | |
| SCHEMBL264320 | 0.88 | SYK (0.44) | CTSLSYKCTRB1CTSBCTSS | |
| SCHEMBL264174 | 0.87 | SYK (0.47) | CTSLSYKCTRB1CTSBCTSS | |
| SCHEMBL5724195 | 0.87 | SYK (0.52) | CTSLSYKCTRB1CTSBCTSS | |
| SCHEMBL5724356 | 0.84 | SYK (0.49) | CTSLSYKCTRB1CTSBCTSS | |
| SCHEMBL5724348 | 0.84 | SYK (0.57) | CTSLSYKCTRB1CTSBCTSS | |
| SCHEMBL262468 | 0.83 | SYK (0.44) | CTSLSYKCTRB1CTSBCTSS | |
| SCHEMBL263531 | 0.83 | SYK (0.47) | CTSLSYKCTRB1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133908-B2 | Heteroaryl derivatives of N-{[(1S,4S,6S)-3-(2-pyridinylcarbonyl)-3-azabicyclo[4.1.0]hept-4-yl]methyl}-2-amine | GLAXO GROUP LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |