SCHEMBL26247007

SCHEMBL26247007

CCC1CCCc2c1n(Cc1cccc(C(N)=O)c1)c1ccccc21

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TBXA2R P21731 14/20 0.55
▸ PTGDR Q13258 10/20 0.55
▸ FABP4 P15090 1/20 0.51
▸ F10 P00742 4/20 0.45
▸ TBXAS1 P24557 1/20 0.42
▸ PDE2A O00408 1/20 0.42
▸ HDAC2 Q92769 1/20 0.42
▸ HDAC8 Q9BY41 1/20 0.42
▸ HDAC6 Q9UBN7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30573130 0.88 FABP4 (0.66) TBXA2RPTGDRFABP4PDE2A
SCHEMBL24155321 0.88 FABP4 (0.66) TBXA2RPTGDRFABP4PDE2A
SCHEMBL25935932 0.85 FABP4 (0.54) TBXA2RPTGDRFABP4F10PDE2A
SCHEMBL30317268 0.82 FABP4 (0.63) TBXA2RPTGDRFABP4
SCHEMBL28983470 0.81 FABP4 (0.57) TBXA2RPTGDRFABP4PDE2A
SCHEMBL30317536 0.81 FABP4 (0.57) TBXA2RPTGDRFABP4PDE2A
SCHEMBL28983479 0.79 FABP4 (0.62) TBXA2RPTGDRFABP4
SCHEMBL26246952 0.78 FABP4 (0.51) FABP4F10HDAC6
SCHEMBL30317431 0.77 FABP4 (0.64) TBXA2RPTGDRFABP4
SCHEMBL28983430 0.75 FABP4 (0.67) FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331673-A1 COMPOSITION OF COMPOUNDS THAT MODULATE CELL METABOLISM AND METHODS OF USE CRESCENTA BIOSCIENCES (US) 2023-10-19 — — US disclosed
US-20230255933-A1 ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS CRESCENTA BIOSCIENCES (US) 2023-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331673-A1 COMPOSITION OF COMPOUNDS THAT MODULATE CELL METABOLISM AND METHODS OF USE FABP4, FABP1, FABP3 TBXA2R 590/4885PTGDR 770/4885FABP4 1/4885
US-20230255933-A1 ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS FABP1, FABP4, FABP5 TBXA2R 1424/4885PTGDR 2965/4885FABP4 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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