Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.43 |
| ▸ | PI4KA | P42356 | 3/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24197042 | 0.96 | YTHDC1 (0.53) | YTHDC1MAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL24197039 | 0.80 | ADORA2A (0.60) | MAPTALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL26255159 | 0.77 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL26255178 | 0.77 | YTHDC1 (0.58) | YTHDC1SMN1; SMN2RAB9ANPC1ADORA2A | |
| SCHEMBL24197041 | 0.77 | YTHDC1 (0.52) | YTHDC1SMN1; SMN2RAB9ANPC1ADORA2A | |
| SCHEMBL26255175 | 0.76 | YTHDC1 (0.59) | YTHDC1SMN1; SMN2RAB9ANPC1ADORA2A | |
| SCHEMBL24197135 | 0.74 | YTHDC1 (0.64) | YTHDC1ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL26255182 | 0.74 | YTHDC1 (0.60) | YTHDC1SMN1; SMN2RAB9ANPC1ADORA2A | |
| Hydrochloric Acid SCHEMBL27438627 | 0.74 | TSHR (0.50) | YTHDC1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL26255179 | 0.73 | YTHDC1 (0.63) | YTHDC1SMN1; SMN2RAB9AKMT2AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279006-A1 | NOVEL COMPOUNDS AND METHODS FOR INCREASING KLOTHO GENE EXPRESSION | KLOTHO THERAPEUTICS, INC. | 2023-09-07 | — | — | US | disclosed |
| US-20230279006-A1 | NOVEL COMPOUNDS AND METHODS FOR INCREASING KLOTHO GENE EXPRESSION | KLOTHO THERAPEUTICS, INC. | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279006-A1 | NOVEL COMPOUNDS AND METHODS FOR INCREASING KLOTHO GENE EXPRESSION | KLKB1, KLK2, KLK1 | YTHDC1 2838/4885MAPT 4363/4885ALDH1A1 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.