Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 17/20 | 0.76 |
| ▸ | PDE3A | Q14432 | 17/20 | 0.76 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 2/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286065 | 0.89 | PDE3B (0.71) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL22130281 | 0.88 | PDE3B (0.70) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL22130282 | 0.88 | PDE3B (0.70) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| Simendan SCHEMBL80460 | 0.86 | PDE3B (1.00) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| Levosimendan SCHEMBL1818300 | 0.86 | PDE3B (1.00) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| Levosimendan SCHEMBL7417215 | 0.86 | PDE3B (1.00) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL22130244 | 0.86 | PDE3B (0.71) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| Levosimendan SCHEMBL83243 | 0.86 | PDE3B (1.00) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL24707001 | 0.86 | PDE3B (0.67) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL22130224 | 0.86 | PDE3B (0.67) | PDE3BPDE3ATNNC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760730-B2 | Process for the preparation of high purity Levosimendan | NAVINTA, LLC (US) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760730-B2 | Process for the preparation of high purity Levosimendan | SRD5A2, SRD5A1, TNNC1 | PDE3B 181/4885PDE3A 144/4885TNNC1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.