⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127898 | 1.00 | — | — | |
| SCHEMBL10035514 | 1.00 | — | — | |
| SCHEMBL278804 | 1.00 | — | — | |
| SCHEMBL1127899 | 1.00 | — | — | |
| SCHEMBL16539999 | 0.96 | LMNA (0.39) | — | |
| SCHEMBL15973517 | 0.88 | CYP2C9 (0.53) | — | |
| SCHEMBL17491564 | 0.87 | CYP2C9 (0.32) | — | |
| SCHEMBL771200 | 0.77 | CYP2C9 (0.35) | — | |
| SCHEMBL24477655 | 0.77 | — | — | |
| SCHEMBL8417560 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230285570-A1 | THERAPEUTICALLY USEFUL CURE-PRO MOLECULES FOR E3 LIGASE MEDIATED DEGRADATION OF PROTEINS, AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY | 2023-09-14 | — | — | US | disclosed |
| US-20230277553-A1 | THERAPEUTIC COMPOSITION OF CURE-PRO COMPOUNDS FOR TARGETED DEGRADATION OF BET DOMAIN PROTEINS, AND METHODS OF MAKING AND USAGE | CORNELL UNIVERSITY | 2023-09-07 | — | — | US | disclosed |