⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24340622 | 0.86 | TDP1 (0.31) | — | |
| SCHEMBL24340597 | 0.81 | — | — | |
| SCHEMBL24340877 | 0.77 | — | — | |
| SCHEMBL26034793 | 0.77 | — | — | |
| SCHEMBL27383486 | 0.76 | MEN1 (0.31) | — | |
| SCHEMBL26035966 | 0.74 | — | — | |
| SCHEMBL24340876 | 0.74 | — | — | |
| SCHEMBL24340596 | 0.73 | — | — | |
| SCHEMBL26037644 | 0.72 | — | — | |
| SCHEMBL25844866 | 0.71 | ESR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265430-A1 | RNAi Agents for Inhibiting Expression of DUX4, Compositions Thereof, And Methods of Use | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2023-08-24 | — | — | US | disclosed |