⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24340622 | 0.86 | TDP1 (0.31) | — | |
| SCHEMBL24340597 | 0.81 | — | — | |
| SCHEMBL26259196 | 0.73 | — | — | |
| SCHEMBL24340877 | 0.72 | — | — | |
| SCHEMBL26049504 | 0.71 | MEN1 (0.35) | — | |
| SCHEMBL24340838 | 0.69 | CAPN1 (0.36) | — | |
| SCHEMBL23418149 | 0.69 | MEN1 (0.44) | — | |
| SCHEMBL26035703 | 0.68 | — | — | |
| SCHEMBL22814733 | 0.67 | MEN1 (0.41) | — | |
| SCHEMBL25789921 | 0.66 | TDP1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022056273-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |