Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MVD | P53602 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471602 | 0.88 | MVD (0.42) | MVDDNM1CHRM2CHRM4CHRM5 | |
| SCHEMBL27703224 | 0.86 | MVD (0.41) | MVDDNM1CHRM2CHRM4CHRM5 | |
| SCHEMBL17817012 | 0.85 | LPAR3 (0.58) | DNM1LPAR3LPAR1LPAR2S1PR2 | |
| SCHEMBL24021282 | 0.85 | LPAR3 (0.58) | DNM1LPAR3LPAR1LPAR2S1PR2 | |
| SCHEMBL14355841 | 0.85 | LPAR3 (0.58) | DNM1LPAR3LPAR1LPAR2S1PR2 | |
| SCHEMBL497177 | 0.84 | LPAR3 (0.46) | LPAR3LPAR1LPAR2MEN1KMT2A | |
| SCHEMBL13521069 | 0.84 | MVD (0.47) | MVDCHRNB2CHRNA4LPAR3LPAR1 | |
| SCHEMBL14750297 | 0.83 | MVD (0.42) | MVDDNM1CHRM2CHRM4CHRM5 | |
| SCHEMBL11754891 | 0.82 | LPAR3 (0.44) | LPAR3LPAR1LPAR2MEN1KMT2A | |
| SCHEMBL7005822 | 0.82 | LPAR3 (0.44) | LPAR3LPAR1LPAR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136087-A1 | PHOSPHORYLCHOLINE-BASED AMPHIPHILIC SILICONES FOR MEDICAL APPLICATIONS | DSM IP ASSETS B.V. (NL) | 2012-05-31 | — | — | US | disclosed |
| EP-2444448-A1 | Phosphorylcholine-based amphiphilic silicones for medical applications | DSM IP Assets B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| US-7413806-B2 | Implant coatings | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136087-A1 | PHOSPHORYLCHOLINE-BASED AMPHIPHILIC SILICONES FOR MEDICAL APPLICATIONS | PHOSPHO1, SGMS1, PLA2G2C | MVD 4642/4885DNM1 3298/4885CHRM2 2363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.