Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MVD | P53602 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703224 | 0.98 | MVD (0.41) | MVDPPARDCHRM2CHRM4CHRM5 | |
| SCHEMBL17676824 | 0.88 | ALDH1A1 (0.39) | MVDPPARDTSHRGGPS1CA12 | |
| SCHEMBL2628074 | 0.88 | MVD (0.42) | MVDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14365954 | 0.84 | MVD (0.47) | MVDPPARDTSHRACHETP53 | |
| SCHEMBL14750297 | 0.83 | MVD (0.42) | MVDPPARDCHRM2CHRM4CHRM5 | |
| SCHEMBL12914746 | 0.82 | TSHR (0.48) | PPARDTSHRTP53TDP1CA12 | |
| SCHEMBL24021282 | 0.81 | LPAR3 (0.58) | DNM1LPAR1LPAR3 | |
| SCHEMBL17817012 | 0.81 | LPAR3 (0.58) | DNM1LPAR1LPAR3 | |
| SCHEMBL14355841 | 0.81 | LPAR3 (0.58) | DNM1LPAR1LPAR3 | |
| SCHEMBL8232301 | 0.81 | MVD (0.43) | MVDCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598500-B1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | RIGEL PHARMACEUTICALS INC (US) | 2021-05-19 | — | — | EP | disclosed |
| US-9920041-B2 | Compositions and methods for inhibition of the JAK pathway | RIGEL PHARMACEUTICALS, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170158683-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | RIGEL PHARMACEUTICALS, INC. (US) | 2017-06-08 | — | — | US | disclosed |
| US-9611260-B2 | Compositions and methods for inhibition of the JAK pathway | RIGEL PHARMACEUTICALS, INC. (US) | 2017-04-04 | — | — | US | disclosed |
| US-20160022622-A1 | LIPID COMPOSITIONS CONTAINING BIOACTIVE FATTY ACIDS | SCIADONICS, INC. | 2016-01-28 | — | — | US | disclosed |
| US-20160024125-A1 | NATURAL LIPIDS CONTAINING NON-OXIDIZABLE FATTY ACIDS | BERGEN TEKNOLOGIOVERFØRING AS (NO) | 2016-01-28 | — | — | US | disclosed |
| US-20150259332-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | RIGEL PHARMACEUTICALS, INC. (US) | 2015-09-17 | — | — | US | disclosed |
| US-9067925-B2 | Compositions and methods for inhibition of the JAK pathway | RIGEL PHARMACEUTICALS, INC. (US) | 2015-06-30 | — | — | US | disclosed |
| EP-2711369-A1 | Liposomes containing tetraether lipid derivatives | Bernina Plus GmbH (DE) | 2014-03-26 | — | — | EP | disclosed |
| US-20130090310-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | RIGEL PHARMACEUTICALS, INC. (US) | 2013-04-11 | — | — | US | disclosed |
| US-20090047596-A1 | Donor element with release-modifier for thermal transfer | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-02-19 | — | — | US | disclosed |
| US-7387864-B2 | Donor element for thermal transfer | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
| US-20080090169-A1 | Composite Film Suitable as a Donor Support in a Radiation-Induced Thermal Transfer Imaging Process | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (DE) | 2008-04-17 | — | — | US | disclosed |
| US-20080003519-A1 | Donor Element for Thermal Transfer | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-01-03 | — | — | US | disclosed |
| EP-1805035-A1 | COMPOSITE FILM SUITABLE AS A DONOR SUPPORT IN A RADIATION-INDUCED THERMAL TRANSFER IMAGING PROCESS | Dupont Teijin Films U.S. Limited Partnership (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1805034-A1 | DONOR ELEMENT FOR THERMAL TRANSFER | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1802471-A1 | DONOR ELEMENT FOR RADIATION-INDUCED THERMAL TRANSFER | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006043072-A1 | COMPOSITE FILM SUITABLE AS A DONOR SUPPORT IN A RADIATION-INDUCED THERMAL TRANSFER IMAGING PROCESS | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) | 2006-04-27 | — | — | WO | disclosed |
| WO-2006045083-A1 | DONOR ELEMENT FOR RADIATION-INDUCED THERMAL TRANSFER | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-04-27 | — | — | WO | disclosed |
| WO-2006045085-A1 | DONOR ELEMENT FOR THERMAL TRANSFER | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259332-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | JAK3, JAK2, JAK1 | MVD 1723/4885PPARD 3635/4885CHRM2 4857/4885 |
| US-20160024125-A1 | NATURAL LIPIDS CONTAINING NON-OXIDIZABLE FATTY ACIDS | FASN, ELOVL1, FADS1 | MVD 1948/4885PPARD 287/4885CHRM2 4805/4885 |
| US-20130090310-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | JAK3, JAK2, JAK1 | MVD 1723/4885PPARD 3635/4885CHRM2 4857/4885 |
| US-20170158683-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | JAK3, JAK2, JAK1 | MVD 1723/4885PPARD 3635/4885CHRM2 4857/4885 |
| US-20160022622-A1 | LIPID COMPOSITIONS CONTAINING BIOACTIVE FATTY ACIDS | ALOX5, ALOX15B, FASN | MVD 939/4885PPARD 710/4885CHRM2 3242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.