Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 4/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508991 | 0.92 | TLR8 (0.52) | TLR8MAPTHSD11B1MRGPRX4KDM4E | |
| SCHEMBL2628138 | 0.85 | TLR8 (0.47) | TLR8MAPTHSD11B1MRGPRX4EZH2 | |
| SCHEMBL14827159 | 0.82 | TLR8 (0.46) | TLR8MAPTHSD11B1MRGPRX4KDM4E | |
| SCHEMBL2628135 | 0.81 | MAPT (0.53) | TLR8MAPTHSD11B1MRGPRX4KDM4E | |
| SCHEMBL2628139 | 0.80 | TLR8 (0.48) | TLR8MAPTHSD11B1MRGPRX4EZH2 | |
| SCHEMBL3138718 | 0.80 | TLR8 (0.53) | TLR8MAPTHSD11B1MRGPRX4KDM4E | |
| SCHEMBL11755731 | 0.80 | SLC6A3 (0.49) | TLR8MAPTMRGPRX4EZH2RHEB | |
| SCHEMBL2628132 | 0.79 | TLR8 (0.45) | TLR8MAPTHSD11B1MRGPRX4CASR | |
| SCHEMBL2628133 | 0.79 | TLR8 (0.45) | TLR8MAPTHSD11B1MRGPRX4CASR | |
| SCHEMBL12780756 | 0.79 | TLR8 (0.67) | TLR8MAPTHSD11B1MRGPRX4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163406-B2 | Membrane-electrode assembly for solid polymer electrolyte fuel cell | HONDA MOTOR CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20080160381-A1 | MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL | HONDA MOTOR CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |