Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | GRM5 | P41594 | 9/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2631777 | 0.89 | MAOB (0.64) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL7962215 | 0.86 | MAOB (0.40) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL29676831 | 0.79 | MAOB (0.51) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL30038594 | 0.79 | MAOB (0.51) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL989822 | 0.79 | MAOB (0.51) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL11065204 | 0.79 | MAOB (0.51) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL6209577 | 0.79 | MAOB (0.51) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL29756757 | 0.79 | MAOB (0.81) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL20165294 | 0.79 | MAOB (0.81) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL915230 | 0.79 | MAOB (0.51) | MAOBMAOAGRM5NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245027-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-04-25 | — | — | EP | disclosed |