Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26476752 | 0.86 | MCHR1 (0.35) | MCHR1 | |
| SCHEMBL26242741 | 0.85 | — | — | |
| SCHEMBL9613620 | 0.85 | — | — | |
| SCHEMBL15683013 | 0.85 | — | — | |
| SCHEMBL20177920 | 0.82 | — | — | |
| SCHEMBL16282709 | 0.79 | — | — | |
| SCHEMBL13767796 | 0.79 | — | — | |
| SCHEMBL10136550 | 0.78 | TRPM8 (0.37) | L3MBTL1TRPA1TRPM8CYP19A1 | |
| SCHEMBL18371930 | 0.78 | TRPM8 (0.37) | L3MBTL1TRPA1TRPM8CYP19A1 | |
| SCHEMBL18371931 | 0.78 | TRPM8 (0.37) | L3MBTL1TRPA1TRPM8CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172737-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2023077046-A1 | INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2023-05-04 | — | — | WO | disclosed |