Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | HTR6 | P50406 | 3/20 | 0.58 |
| ▸ | HTR3A | P46098 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.58 |
| ▸ | HTR3B | O95264 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.58 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.52 |
| ▸ | BRD1 | O95696 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 8/20 | 0.48 |
| ▸ | HTR2B | P41595 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25407437 | 1.00 | DRD2 (0.58) | DRD2HTR6HTR3ADRD3HTR3E | |
| SCHEMBL26288599 | 1.00 | DRD2 (0.58) | DRD2HTR6HTR3ADRD3HTR3E | |
| SCHEMBL21461788 | 0.87 | HTR2C (0.48) | DRD2HTR6HTR3ADRD3HTR3E | |
| SCHEMBL19709338 | 0.87 | HTR2C (0.48) | DRD2HTR6HTR3ADRD3HTR3E | |
| SCHEMBL8911452 | 0.84 | DRD2 (0.56) | DRD2HTR6HTR3ADRD3HTR3E | |
| SCHEMBL30506635 | 0.84 | DRD2 (0.56) | DRD2HTR6HTR3ADRD3HTR3E | |
| SCHEMBL21359240 | 0.83 | HTR2C (0.47) | DRD2HTR6BRPF1BRD1BRD4 | |
| SCHEMBL19709331 | 0.83 | HTR2C (0.47) | DRD2HTR6BRPF1BRD1BRD4 | |
| SCHEMBL21359242 | 0.83 | HTR2C (0.47) | DRD2HTR6BRPF1BRD1BRD4 | |
| SCHEMBL30952461 | 0.83 | HTR2C (0.47) | DRD2HTR6BRPF1BRD1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279008-A1 | PTGR2 INHIBITORS AND THEIR USE | NATIONAL TAIWAN UNIVERSITY (TW) | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279008-A1 | PTGR2 INHIBITORS AND THEIR USE | PTGFR, PTGIR, PTGDR2 | DRD2 924/4885HTR6 527/4885HTR3A 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.