Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 8/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | AHCY | P23526 | 3/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26290018 | 0.90 | P2RY1 (0.62) | P2RY1P2RY2P2RY11ENPP1P2RX1 | |
| SCHEMBL31652871 | 0.89 | P2RY1 (0.48) | P2RY1P2RY2CA5AP2RY11ENPP1 | |
| SCHEMBL30590475 | 0.87 | P2RY1 (0.48) | P2RY1P2RY2CA5AP2RY11ENPP1 | |
| SCHEMBL19211131 | 0.87 | P2RY1 (0.48) | P2RY1P2RY2CA5AP2RY11ENPP1 | |
| SCHEMBL26289786 | 0.86 | CA5A (0.47) | P2RY1P2RY2CA5AP2RY11ENPP1 | |
| SCHEMBL25565236 | 0.85 | P2RY1 (0.48) | P2RY1P2RY2CA5AP2RY11ENPP1 | |
| SCHEMBL19993659 | 0.84 | POLB (0.57) | P2RY1P2RY2P2RY6NT5E | |
| SCHEMBL25565235 | 0.84 | CA5A (0.48) | P2RY1P2RY2CA5AP2RY11ENPP1 | |
| SCHEMBL21100303 | 0.83 | P2RY1 (0.52) | P2RY1P2RY2CA5AP2RY11ENPP1 | |
| SCHEMBL24727781 | 0.81 | ADORA2A (0.46) | CA5ANT5EAHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178128-A1 | METHODS OF TREATING MEDICAL CONDITIONS USING ISLATRAVIR OR A RELATED COMPOUND | ROME THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |