Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.73 |
| ▸ | MEN1 | O00255 | 12/20 | 0.73 |
| ▸ | POLB | P06746 | 11/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.73 |
| ▸ | MAPT | P10636 | 9/20 | 0.73 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.73 |
| ▸ | BLM | P54132 | 7/20 | 0.73 |
| ▸ | PKM | P14618 | 6/20 | 0.73 |
| ▸ | HPGD | P15428 | 5/20 | 0.73 |
| ▸ | THRB | P10828 | 4/20 | 0.73 |
| ▸ | RECQL | P46063 | 4/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.73 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | APEX1 | P27695 | 4/20 | 0.72 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 2/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26293052 | 0.86 | MEN1 (0.71) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL13856578 | 0.85 | MEN1 (1.00) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL13856429 | 0.84 | MEN1 (1.00) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL26295615 | 0.81 | KMT2A (0.75) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL26294993 | 0.79 | MEN1 (0.73) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL13856422 | 0.79 | MEN1 (1.00) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL26294531 | 0.79 | MEN1 (0.76) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL26294624 | 0.78 | MEN1 (0.86) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL26293182 | 0.78 | MEN1 (0.82) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL26293058 | 0.77 | MEN1 (0.78) | KMT2AMEN1POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168240-A1 | SMALL MOLECULE INHIBITORS OF ENPP1 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-07 | — | — | WO | disclosed |