Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 14/20 | 1.00 |
| ▸ | MAPT | P10636 | 12/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 9/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 1.00 |
| ▸ | PKM | P14618 | 7/20 | 1.00 |
| ▸ | BLM | P54132 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | RECQL | P46063 | 6/20 | 1.00 |
| ▸ | THRB | P10828 | 6/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 1.00 |
| ▸ | NR4A1 | P22736 | 4/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 3/20 | 1.00 |
| ▸ | BID | P55957 | 1/20 | 1.00 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 11/20 | 0.82 |
| ▸ | LMNA | P02545 | 2/20 | 0.82 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15814086 | 0.91 | MEN1 (0.84) | MEN1KMT2AMAPTALDH1A1MCL1 | |
| SCHEMBL13856578 | 0.90 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1MCL1 | |
| SCHEMBL26293058 | 0.88 | MEN1 (0.78) | MEN1KMT2AMAPTALDH1A1MCL1 | |
| SCHEMBL13856429 | 0.84 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1MCL1 | |
| SCHEMBL30518187 | 0.84 | MEN1 (0.72) | MEN1KMT2AMAPTALDH1A1MCL1 | |
| SCHEMBL20919142 | 0.84 | MEN1 (0.72) | MEN1KMT2AMAPTALDH1A1MCL1 | |
| SCHEMBL6722302 | 0.84 | MCL1 (0.77) | MEN1KMT2AMAPTALDH1A1MCL1 | |
| SCHEMBL1895132 | 0.84 | MEN1 (0.77) | MEN1KMT2AMAPTALDH1A1MCL1 | |
| SCHEMBL26294531 | 0.84 | MEN1 (0.76) | MEN1KMT2AMAPTALDH1A1MCL1 | |
| SCHEMBL26293052 | 0.83 | MEN1 (0.71) | MEN1KMT2AMAPTALDH1A1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365540-A1 | SMALL MOLECULE INHIBITORS OF ENPP1 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-16 | — | — | US | disclosed |
| US-20230365540-A1 | SMALL MOLECULE INHIBITORS OF ENPP1 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-16 | — | — | US | disclosed |
| WO-2022056068-A1 | SMALL MOLECULE INHIBITORS OF ENPP1 | THE REGENTS OF THE UNIVERSITY OFCALIFORNIA (US) | 2022-03-17 | — | — | WO | disclosed |
| EP-3285583-B1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | UNIV MICHIGAN REGENTS (US) | 2021-03-17 | — | — | EP | disclosed |
| US-9884841-B2 | Small molecule inhibitors of Mcl-1 and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-02-06 | — | — | US | disclosed |
| US-9884841-B2 | Small molecule inhibitors of Mcl-1 and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-02-06 | — | — | US | disclosed |
| WO-2016172218-A1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-10-27 | — | — | WO | disclosed |
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | BCL2, BAX, BAD | MEN1 4323/4885KMT2A 4047/4885MAPT 3866/4885 |
| US-20230365540-A1 | SMALL MOLECULE INHIBITORS OF ENPP1 | ENPP1, ENPP2, ENPP3 | MEN1 2065/4885KMT2A 4317/4885MAPT 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.