SCHEMBL262972

SCHEMBL262972

CCC(Br)C(=O)Oc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
CYP1A2 P05177 1/20 0.47
ELANE P08246 2/20 0.45
MAPT P10636 3/20 0.44
ESR1 P03372 1/20 0.42
HIF1A Q16665 1/20 0.42
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 2/20 0.40
POLB P06746 1/20 0.40
MIF P14174 1/20 0.40
FAAH O00519 1/20 0.40
HPGD P15428 2/20 0.39
TSHR P16473 1/20 0.39
THRB P10828 1/20 0.39
PIN1 Q13526 1/20 0.39
ALOX15 P16050 1/20 0.38
RAB9A P51151 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9849997 0.83 ATM (0.46) ATML3MBTL1CYP1A2ELANEMAPT
SCHEMBL27527798 0.83 ZDHHC7 (0.47) ATML3MBTL1ALDH1A1TDP1FAAH
SCHEMBL19105214 0.81 ATM (0.51) ATML3MBTL1CYP1A2ELANEMAPT
SCHEMBL650209 0.81 ATM (0.51) ATML3MBTL1CYP1A2ELANEMAPT
SCHEMBL27916296 0.81 CYP1A2 (0.47) ATML3MBTL1CYP1A2ELANEMAPT
SCHEMBL7773448 0.80 ZDHHC7 (0.57) ALDH1A1TDP1FAAHTSHR
SCHEMBL11078891 0.80 PPARG (0.43) ATMESR1ALDH1A1KMT2ATDP1
SCHEMBL7062133 0.80 ATM (0.44) ATML3MBTL1CYP1A2ELANEMAPT
SCHEMBL14996055 0.79 ELANE (0.50) ATML3MBTL1CYP1A2ELANEMAPT
SCHEMBL650639 0.79 ELANE (0.50) ATML3MBTL1CYP1A2ELANEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4309002-A1 RECORDING A LATENT HOLOGRAPHIC GRATING AND AMPLIFICATION OF ITS DYNAMIC RANGE META PLATFORMS TECHNOLOGIES, LLC (US) 2024-01-24 EP claimed
US-11541599-B2 3-D printing components using two-light sources to control location of solidification FORD GLOBAL TECHNOLOGIES, LLC (US) 2023-01-03 US disclosed
US-11091484-B2 Tricyclic heterocycles as BET protein inhibitors INCYTE CORPORATION (US) 2021-08-17 US disclosed
US-20210162670-A1 3-D PRINTING COMPONENTS USING TWO-LIGHT SOURCES TO CONTROL LOCATION OF SOLIDIFICATION FORD GLOBAL TECHNOLOGIES, LLC 2021-06-03 US disclosed
CN-109134749-B Preparation method of super-hydrophobic anti-corrosion material containing azide group 江南大学 2020-02-18 CN disclosed
US-10442803-B2 Tricyclic heterocycles as bet protein inhibitors INCYTE CORPORATION (US) 2019-10-15 US disclosed
US-20180002334-A1 TRICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS INCYTE CORPORATION 2018-01-04 US disclosed
EP-2443485-B1 BIOMEDICAL DEVICES BAUSCH & LOMB (US) 2017-11-08 EP disclosed
US-9777003-B2 Tricyclic heterocycles as bet protein inhibitors INCYTE CORPORATION (US) 2017-10-03 US disclosed
EP-2443482-B1 BIOMEDICAL DEVICES, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING THE SAME. BAUSCH & LOMB (US) 2017-03-01 EP disclosed
US-6288086-B1 COMPOUNDS SUCH AS 1-METHYL-4-(4-BUTOXY-BENZENESULFONYL) -PIPERIDINE-4-CARBOXYLIC ACID HYDROXYAMIDE USED TO TREAT ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, ETC.; LOW MOLECULAR WEIGHT AND NON-PEPTIDAL AMERICAN CYANAMID COMPANY 2001-09-11 US disclosed
WO-2001025265-A1 METAL-BINDING COMPOUNDS AND USES THEREFOR DMI BIOSCIENCES, INC. (US) 2001-04-12 WO disclosed
US-6172057-B1 ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS; ANTITUMOR AGENTS AMERICAN CYANAMID COMPANY 2001-01-09 US disclosed
EP-0973512-A1 N-HYDROXY-2-(ALKYL, ARYL OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS American Cyanamid Company (US) 2000-01-26 EP disclosed
WO-1998037877-A1 N-HYDROXY-2-(ALKYL, ARYL OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS AMERICAN CYANAMID COMPANY (US) 1998-09-03 WO disclosed
US-4987140-A ANTIINFLAMMATORY, ANTIRHEUMATIC ROUSSEL UCLAF (FR) 1991-01-22 US disclosed
US-4925859-A Novel 4-hydroxy-3-pyridine-carboxamides useful for treating inflammation and rheumatism ROUSSEL UCLAF (FR) 1990-05-15 US disclosed
US-4820715-A TREATING NAUSEA AND GASTRIC DISORDERS BRISTOL-MYERS COMPANY (US) 1989-04-11 US disclosed
US-4808624-A ANTIEMETICS BRISTOL-MYERS COMPANY (US) 1989-02-28 US disclosed
US-4153724-A Benzoyl phenoxy acetic acid derivatives KAKEN CHEMICAL CO., LTD. (JP) 1979-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180002334-A1 TRICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS BRD1, BRD3, BRD2 ATM 2387/4885L3MBTL1 697/4885CYP1A2 3768/4885
US-10442803-B2 Tricyclic heterocycles as bet protein inhibitors BRD1, BRD3, BRD2 ATM 2387/4885L3MBTL1 697/4885CYP1A2 3768/4885
US-11091484-B2 Tricyclic heterocycles as BET protein inhibitors BRD1, BRD3, BRD2 ATM 2387/4885L3MBTL1 697/4885CYP1A2 3768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.