Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.57 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436169 | 0.96 | ZDHHC2 (0.61) | ZDHHC7ZDHHC2LCKPPARDZDHHC20 | |
| SCHEMBL27527798 | 0.94 | ZDHHC7 (0.47) | ZDHHC7ZDHHC2LCKPPARDZDHHC20 | |
| SCHEMBL29163411 | 0.84 | ZDHHC2 (0.49) | ZDHHC2PRSS1PRSS2PRSS3FAAH | |
| SCHEMBL7732099 | 0.84 | TDP1 (0.55) | ZDHHC2PRSS1PRSS2PRSS3FAAH | |
| SCHEMBL3929624 | 0.84 | ZDHHC2 (0.49) | ZDHHC2PRSS1PRSS2PRSS3FAAH | |
| SCHEMBL7734011 | 0.84 | TDP1 (0.55) | ZDHHC2PRSS1PRSS2PRSS3FAAH | |
| SCHEMBL11296486 | 0.84 | ZDHHC2 (0.49) | ZDHHC2PRSS1PRSS2PRSS3FAAH | |
| SCHEMBL7970865 | 0.84 | ELANE (0.41) | ZDHHC7PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL28487778 | 0.83 | ZDHHC2 (0.42) | ZDHHC7ZDHHC2LCKPPARDZDHHC20 | |
| SCHEMBL9275820 | 0.83 | ZDHHC7 (0.46) | ZDHHC7ZDHHC2LCKPPARDZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587639-B1 | PHARMACEUTICAL COMPOSITIONS | LIPOXEN LTD (GB) | 2001-08-16 | — | — | EP | disclosed |
| US-5846951-A | Pharmaceutical compositions | THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 1998-12-08 | — | — | US | disclosed |
| EP-0587639-A1 | PHARMACEUTICAL COMPOSITIONS | THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 1994-03-23 | — | — | EP | disclosed |
| WO-1992022331-A1 | PHARMACEUTICAL COMPOSITIONS | THE SCHOOL OF PHARMACY (GB) | 1992-12-23 | — | — | WO | disclosed |