Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26300363 | 0.94 | CYP2C8 (0.42) | CYP2C8SRD5A2CES2CES1KDM1A | |
| SCHEMBL26300393 | 0.94 | BACE1 (0.45) | CYP2C8SRD5A2BACE1FNTAFNTB | |
| SCHEMBL26300513 | 0.94 | BACE1 (0.45) | CYP2C8SRD5A2BACE1PSEN1PSEN2 | |
| SCHEMBL26300425 | 0.91 | PTGDR2 (0.47) | CYP2C8 | |
| SCHEMBL26300627 | 0.91 | PTGDR2 (0.47) | CYP2C8 | |
| SCHEMBL26300469 | 0.91 | BAZ2B (0.48) | CYP2C8SRD5A2KDM1ABACE1SCN5A | |
| SCHEMBL26300379 | 0.90 | AKR1C3 (0.41) | CYP2C8SRD5A2CES2CES1KDM1A | |
| SCHEMBL26300565 | 0.88 | FNTA (0.47) | SRD5A2CES2BACE1FNTAFNTB | |
| SCHEMBL26300717 | 0.88 | PTGDR2 (0.46) | BACE1 | |
| SCHEMBL26301296 | 0.86 | FNTA (0.51) | CYP2C8SRD5A2BACE1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4233864-A1 | INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT | Ajou University Industry-Academic Cooperation Foundation (KR) | 2023-08-30 | — | — | EP | disclosed |