SCHEMBL26301296

SCHEMBL26301296

O=C(c1ccc(C(F)(F)F)cc1)c1cc(-c2ccc(C(F)(F)F)cc2)c2ccccn12

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 7/20 0.51
▸ FNTB P49356 7/20 0.51
▸ BAZ2B Q9UIF8 4/20 0.48
▸ BAZ2A Q9UIF9 4/20 0.48
▸ CYP2C8 P10632 1/20 0.47
▸ BACE1 P56817 1/20 0.45
▸ SRD5A2 P31213 1/20 0.43
▸ HIF1A Q16665 1/20 0.41
▸ EPAS1 Q99814 1/20 0.41
▸ RORC P51449 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26301329 0.96 FNTA (0.53) FNTAFNTBBAZ2BBAZ2ACYP2C8
SCHEMBL26301363 0.96 FNTA (0.57) FNTAFNTBBAZ2BBAZ2ACYP2C8
SCHEMBL26301313 0.94 BAZ2B (0.52) FNTAFNTBBAZ2BBAZ2ACYP2C8
SCHEMBL26301353 0.91 BAZ2B (0.63) FNTAFNTBBAZ2BBAZ2ACYP2C8
SCHEMBL26301454 0.91 BAZ2B (0.46) FNTAFNTBBAZ2BBAZ2ABACE1
SCHEMBL26301335 0.91 BAZ2B (0.46) FNTAFNTBBAZ2BBAZ2ABACE1
SCHEMBL26301577 0.88 BAZ2B (0.48) FNTAFNTBBAZ2BBAZ2ACYP2C8
SCHEMBL26300324 0.86 CYP2C8 (0.47) FNTAFNTBCYP2C8BACE1SRD5A2
SCHEMBL26300393 0.86 BACE1 (0.45) FNTAFNTBCYP2C8BACE1SRD5A2
SCHEMBL26300513 0.86 BACE1 (0.45) FNTAFNTBCYP2C8BACE1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
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