Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 3/20 | 0.44 |
| ▸ | FNTB | P49356 | 3/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 6/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 6/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26300911 | 0.95 | BACE1 (0.47) | BACE1FNTAFNTBBAZ2BBAZ2A | |
| SCHEMBL26300877 | 0.94 | CYP2C8 (0.43) | BACE1BAZ2BBAZ2ACYP2C8ALDH1A1 | |
| SCHEMBL26300894 | 0.93 | CYP2C8 (0.42) | BACE1BAZ2BBAZ2ACYP2C8ALDH1A1 | |
| SCHEMBL26300545 | 0.89 | FNTA (0.44) | BACE1FNTAFNTBBAZ2BBAZ2A | |
| SCHEMBL26300513 | 0.88 | BACE1 (0.45) | BACE1FNTAFNTBCYP2C8ALDH1A1 | |
| SCHEMBL26301013 | 0.88 | FNTA (0.49) | FNTAFNTBBAZ2BBAZ2AALDH1A1 | |
| SCHEMBL26302004 | 0.88 | BAZ2B (0.47) | BACE1BAZ2BBAZ2AMAOBAPP | |
| SCHEMBL26301036 | 0.88 | FNTA (0.51) | FNTAFNTBBAZ2BBAZ2AALDH1A1 | |
| SCHEMBL26300949 | 0.87 | BAZ2B (0.51) | BACE1BAZ2BBAZ2ACYP2C8ALDH1A1 | |
| SCHEMBL26301092 | 0.87 | PTPN11 (0.42) | BACE1BAZ2BBAZ2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4233864-A1 | INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT | Ajou University Industry-Academic Cooperation Foundation (KR) | 2023-08-30 | — | — | EP | disclosed |