SCHEMBL26301013

SCHEMBL26301013

CC(=O)c1ccc(-c2cc(C(=O)c3ccccc3)n3ccc(C(C)=O)cc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 6/20 0.49
▸ FNTB P49356 6/20 0.49
▸ BAZ2B Q9UIF8 9/20 0.47
▸ BAZ2A Q9UIF9 9/20 0.47
▸ SMN1; SMN2 Q16637 3/20 0.45
▸ MAPT P10636 2/20 0.45
▸ NPSR1 Q6W5P4 2/20 0.42
▸ POLB P06746 1/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ HPGD P15428 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ GLA P06280 1/20 0.39
▸ BRD4 O60885 1/20 0.39
▸ BRD9 Q9H8M2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26301036 0.95 FNTA (0.51) FNTAFNTBBAZ2BBAZ2ASMN1; SMN2
SCHEMBL26301735 0.91 BAZ2B (0.46) FNTAFNTBBAZ2BBAZ2ASMN1; SMN2
SCHEMBL26301387 0.89 FNTA (0.59) FNTAFNTBBAZ2BBAZ2ASMN1; SMN2
SCHEMBL26301057 0.89 BAZ2B (0.47) FNTAFNTBBAZ2BBAZ2ASMN1; SMN2
SCHEMBL26304108 0.89 BAZ2B (0.62) FNTAFNTBBAZ2BBAZ2ASMN1; SMN2
SCHEMBL26301683 0.89 FNTA (0.46) FNTAFNTBBAZ2BBAZ2AMAPT
SCHEMBL26300978 0.88 BACE1 (0.47) FNTAFNTBBAZ2BBAZ2AALDH1A1
SCHEMBL26301159 0.87 ALDH1A1 (0.48) FNTAFNTBBAZ2BBAZ2ASMN1; SMN2
SCHEMBL26301762 0.86 BAZ2B (0.47) FNTAFNTBBAZ2BBAZ2AMAPT
SCHEMBL26302021 0.86 BAZ2B (0.54) BAZ2BBAZ2ASMN1; SMN2MAPTBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
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