SCHEMBL26301313

SCHEMBL26301313

CC(=O)c1ccc(-c2cc(C(=O)c3ccc(C(F)(F)F)cc3)n3ccccc23)cc1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ BAZ2B Q9UIF8 9/20 0.52
▸ BAZ2A Q9UIF9 9/20 0.52
▸ BACE1 P56817 1/20 0.46
▸ FNTA P49354 6/20 0.46
▸ FNTB P49356 6/20 0.46
▸ BRD4 O60885 2/20 0.43
▸ BRD9 Q9H8M2 2/20 0.43
▸ CYP2C8 P10632 1/20 0.42
▸ BRD2 P25440 1/20 0.41
▸ BRD3 Q15059 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26301296 0.94 FNTA (0.51) BAZ2BBAZ2ABACE1FNTAFNTB
SCHEMBL26301363 0.90 FNTA (0.57) BAZ2BBAZ2ABACE1FNTAFNTB
SCHEMBL26301329 0.90 FNTA (0.53) BAZ2BBAZ2ABACE1FNTAFNTB
SCHEMBL26300894 0.88 CYP2C8 (0.42) BAZ2BBAZ2ABACE1CYP2C8
SCHEMBL26300363 0.88 CYP2C8 (0.42) BAZ2BBAZ2ABACE1FNTAFNTB
SCHEMBL26301387 0.87 FNTA (0.59) BAZ2BBAZ2AFNTAFNTBBRD4
SCHEMBL26302080 0.87 BAZ2B (0.67) BAZ2BBAZ2ABACE1BRD4BRD9
SCHEMBL26301335 0.87 BAZ2B (0.46) BAZ2BBAZ2ABACE1FNTAFNTB
SCHEMBL26301454 0.87 BAZ2B (0.46) BAZ2BBAZ2ABACE1FNTAFNTB
SCHEMBL26300877 0.87 CYP2C8 (0.43) BAZ2BBAZ2ABACE1CYP2C8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
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