SCHEMBL26301618

SCHEMBL26301618

CCN(CC)c1ccc(C(=O)c2cc(-c3ccc(C(C)=O)cc3)c3ccccn23)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BAZ2B Q9UIF8 8/20 0.58
▸ BAZ2A Q9UIF9 8/20 0.58
▸ MAPT P10636 3/20 0.45
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ MCL1 Q07820 2/20 0.45
▸ NOX1 Q9Y5S8 2/20 0.45
▸ POLB P06746 1/20 0.45
▸ GAA P10253 1/20 0.45
▸ BRD4 O60885 1/20 0.44
▸ BRD9 Q9H8M2 1/20 0.44
▸ FNTA P49354 6/20 0.44
▸ FNTB P49356 6/20 0.44
▸ ALDH1A1 P00352 2/20 0.42
▸ NPC1 O15118 2/20 0.42
▸ RAB9A P51151 2/20 0.42
▸ HPGD P15428 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ USP2 O75604 1/20 0.41
▸ TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26301631 0.92 BAZ2B (0.52) BAZ2BBAZ2AMAPTMEN1KMT2A
SCHEMBL26301866 0.92 BAZ2B (0.55) BAZ2BBAZ2AMAPTMEN1KMT2A
SCHEMBL26301662 0.91 BAZ2B (0.65) BAZ2BBAZ2AMAPTBRD4BRD9
SCHEMBL26304348 0.89 MAPT (0.45) BAZ2BBAZ2AMAPTMEN1KMT2A
SCHEMBL26301647 0.88 BAZ2B (0.49) BAZ2BBAZ2AMAPTPOLBGAA
SCHEMBL26301577 0.87 BAZ2B (0.48) BAZ2BBAZ2AMAPTFNTAFNTB
SCHEMBL26301762 0.87 BAZ2B (0.47) BAZ2BBAZ2AMAPTMEN1KMT2A
SCHEMBL26301387 0.85 FNTA (0.59) BAZ2BBAZ2AMAPTBRD4BRD9
SCHEMBL26301287 0.84 BAZ2B (0.52) BAZ2BBAZ2AMAPTMEN1KMT2A
SCHEMBL29547228 0.82 FNTA (0.51) BAZ2BBAZ2AMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
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