SCHEMBL26301287

SCHEMBL26301287

CCN(CC)c1ccc(C(=O)c2cc(-c3ccc(N(C)C)cc3)c3cc(C(C)=O)ccn23)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BAZ2B Q9UIF8 3/20 0.52
▸ BAZ2A Q9UIF9 3/20 0.52
▸ MAPT P10636 6/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ MCL1 Q07820 2/20 0.40
▸ NOX1 Q9Y5S8 2/20 0.40
▸ POLB P06746 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ ALDH1A1 P00352 6/20 0.39
▸ MAPK1 P28482 2/20 0.39
▸ TSHR P16473 2/20 0.39
▸ USP2 O75604 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ HPGD P15428 3/20 0.38
▸ RARB P10826 1/20 0.36
▸ RARG P13631 1/20 0.36
▸ CNR2 P34972 1/20 0.36
▸ NPC1 O15118 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26304348 0.95 MAPT (0.45) BAZ2BBAZ2AMAPTMEN1KMT2A
SCHEMBL26301762 0.90 BAZ2B (0.47) BAZ2BBAZ2AMAPTMEN1KMT2A
SCHEMBL26301245 0.89 SMARCA2 (0.41) BAZ2BBAZ2AMAPTMEN1KMT2A
SCHEMBL26304344 0.88 BAZ2B (0.39) BAZ2BBAZ2AMAPTMEN1KMT2A
SCHEMBL26304108 0.87 BAZ2B (0.62) BAZ2BBAZ2AMAPTALDH1A1HPGD
SCHEMBL26301662 0.86 BAZ2B (0.65) BAZ2BBAZ2AMAPTALDH1A1HPGD
SCHEMBL26300859 0.85 BAZ2B (0.44) BAZ2BBAZ2AMAPTPOLBGAA
SCHEMBL26300949 0.84 BAZ2B (0.51) BAZ2BBAZ2AMAPTGAAALDH1A1
SCHEMBL26302073 0.84 BAZ2B (0.71) BAZ2BBAZ2AMAPTALDH1A1MAPK1
SCHEMBL26301618 0.84 BAZ2B (0.58) BAZ2BBAZ2AMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
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