Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 4/20 | 0.52 |
| ▸ | DNMT3A | Q9Y6K1 | 4/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | DNMT3L | Q9UJW3 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 3/20 | 0.46 |
| ▸ | BCR | P11274 | 3/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.46 |
| ▸ | PRKCA | P17252 | 2/20 | 0.46 |
| ▸ | BRAF | P15056 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26315265 | 0.87 | DNMT1 (0.49) | DNMT1DNMT3AKCNK3KCNK9DNMT3L | |
| SCHEMBL24003860 | 0.85 | DNMT1 (0.49) | DNMT1DNMT3AKCNK3DNMT3LABL1 | |
| SCHEMBL30232699 | 0.85 | DNMT1 (0.49) | DNMT1DNMT3AKCNK3DNMT3LABL1 | |
| SCHEMBL30287679 | 0.85 | DNMT1 (0.54) | DNMT1DNMT3AKCNK3KCNK9DNMT3L | |
| SCHEMBL30232520 | 0.85 | DNMT1 (0.54) | DNMT1DNMT3AKCNK3KCNK9DNMT3L | |
| SCHEMBL24003828 | 0.85 | DNMT1 (0.54) | DNMT1DNMT3AKCNK3KCNK9DNMT3L | |
| SCHEMBL24006113 | 0.85 | DNMT1 (0.54) | DNMT1DNMT3AKCNK3KCNK9DNMT3L | |
| SCHEMBL24003830 | 0.82 | KCNK3 (0.53) | DNMT1DNMT3AKCNK3KCNK9ABL1 | |
| SCHEMBL30232513 | 0.82 | KCNK3 (0.53) | DNMT1DNMT3AKCNK3KCNK9ABL1 | |
| SCHEMBL24004056 | 0.81 | KCNK3 (0.57) | DNMT1DNMT3AKCNK3KCNK9DNMT3L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | DNMT1 4758/4885DNMT3A 4679/4885KCNK3 2395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.